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Diagnosis must then be confirmed through laboratory tests. Miyazaki T, Katagiri H, Kanegae Y, Takayanagi H, Sawada Y, Yamamoto A, et al. 500 may have other alternatives. Substitution of Met-3 with the common Met replacements Leu and norleucine (Nle), compounds 16 and 17, afforded peptides with similar affinity.

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